LifeSmart SEQUENCE

A One-time Comprehensive Assessment of Genetic Health:

Learn what your genes say about your health. LifeSmart SEQUENCE™  is a health and wellness-based genetic test that is useful in many areas of medicine and can improve the medical care you or your family member receives. A onetime test that provides a lifetime of results.

A simple cheek swab can help determine if you are predisposed to certain cancers, heart attacks, and other health risks, even if you are currently healthy. If you are at risk for a genetic disorder, you can make changes to improve your health through genetic sequencing.

What  LifeSmart SEQUENCE™  Looks For?

CARRIER SCREENING

20 Genes

  • Autosomal Recessive Diseases

  • X-Linked Diseases
     

NEURODEGENERATIVE DISEASES

41 Genes 

  • Alzheimer's Disease 

  • Parkinson's  Disease

  • Amyotrophic Lateral Sclerosis
     

WELLNESS

53 Genes

  • Diet / Nutrition

  • Sleep 

  • Fitness / Exercise

HEART DISEASE

122 Genes 

  • Cardiomyopathy

  • Arrhythmia

  • Hereditary Cholesterol Disorder

  • Hypertension

  • Blood Clotting / Vascular Disorders

HEARING LOSS

15 Genes

  • Age-Related Hearing Loss

  • Congenital  Nonsyndromic Hearing Loss

  • Noise Induced Hearing Loss

METABOLIC DISORDERS

14 Genes 

  • Hemochromatosis

  • Risk of Adverse Response to Anesthesia
     

INHERITED CANCERS

86 Genes

  • Hereditary Breast Cancer

  • Hereditary Ovarian Cancer

  • Lynch Syndrome

  • Risks for Brain, Renal, Hematologic, Uterine, Pancreatic, Prostate, and Thyroid Cancers
     

INFERTILITY

Female: 33 Genes
Male:   18 Genes 

  • Low and Absent Sperm Count Disorders

  • Premature Ovarian Failure Disorders

  • PCOS

80 Genes

  • Likelihood of response and risk for adverse reaction to hundreds of the most commonly prescribed drugs

ADVERSE  DRUGS

INTERACTIONS

VISION LOSS

19 Genes 

  • Early Onset Glaucoma

  • Early Onset Macular Degeneration
     

What is "Genetic Sequencing"?

Sequencing is The "deeper dive" to genotyping. Because LifeSmart SEQUENCE™ is a health and wellness test, it employs sequencing. Sequencing is a method used to determine the exact sequence of a certain length of DNA. You can sequence a short piece, the whole genome, or parts of the genome such as the "exome," which are the regions of the genome that contain the instructions for RNAs (ribonucleic acid) and proteins. Depending on the region, a given length of sequence may include some DNA that varies between individuals, in addition to regions that are constant. Therefore, sequencing can be used to genotype someone for known variants, as well as identify variants that may be unique to that person.

 

Not as in-depth, Genotyping is the "basic" process of determining which genetic variants an individual possesses. This type is used by some of the "retail" or "novelty" type products you may be familiar with. Genotyping can be performed through a variety of different methods, depending on the variants of interest and the resources available. For looking at many different variants at once, especially common variants, genotyping chips are an efficient and accurate method. They do, however, require prior identification of the variants of interest.

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